SCHEMBL753994

SCHEMBL753994

CCC(C)(c1ccccc1)C(C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 3/20 0.41
TRPA1 O75762 3/20 0.39
CACNA1F O60840 1/20 0.39
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA2B P18089 1/20 0.39
CHRM3 P20309 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
OPRK1 P41145 1/20 0.39
CACNA1D Q01668 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KCNH2 Q12809 1/20 0.39
CACNA1S Q13698 1/20 0.39
CACNA1C Q13936 1/20 0.39
SCN5A Q14524 1/20 0.39
ESR1 P03372 1/20 0.38
TAAR1 Q96RJ0 3/20 0.38
LMNA P02545 1/20 0.38
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13126735 0.85 KIF11 (0.41) RIPK1KCNH2TAAR1LMNACYP2D6
SCHEMBL13126793 0.84 OPRD1 (0.39) TRPA1ADRA1AESR1LMNA
SCHEMBL11741048 0.81 CYP2C19 (0.42) RIPK1ESR1TAAR1CYP2D6KCNN4
SCHEMBL10893994 0.81 RIPK1 (0.39) RIPK1CACNA1FCHRM2CHRM1ADRA2B
SCHEMBL8677180 0.79 CYP2C19 (0.41) RIPK1TRPA1ESR1TAAR1LMNA
SCHEMBL28312127 0.79 GRIN1 (0.42) RIPK1TRPA1ESR1TAAR1LMNA
SCHEMBL10325656 0.78 LMNA (0.41) RIPK1TRPA1HRH1ESR1TAAR1
SCHEMBL20859677 0.78 TAAR1 (0.39) RIPK1CACNA1FCHRM2CHRM1ADRA2B
SCHEMBL22766210 0.77 RIPK1 (0.45) RIPK1TRPA1CACNA1FCHRM2CHRM1
SCHEMBL68538 0.77 RIPK1 (0.45) RIPK1TRPA1CACNA1FCHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12195397-B2 Geopolymer composite and expandable vinyl aromatic polymer granulate and expanded vinyl aromatic polymer foam comprising the same SYNTHOS S.A. (PL) 2025-01-14 US disclosed
EP-4474413-A2 PROCESS FOR THE PRODUCTION OF EXPANDABLE VINYL AROMATIC POLYMER GRANULATE HAVING DECREASED THERMAL CONDUCTIVITY Synthos S.A. (PL) 2024-12-11 EP disclosed
EP-3245248-B1 PROCESS FOR THE PRODUCTION OF EXPANDABLE VINYL AROMATIC POLYMER GRANULATE HAVING DECREASED THERMAL CONDUCTIVITY Synthos Sa (PL) 2024-09-25 EP disclosed
CN-118027497-A Process for producing expandable vinyl aromatic polymer particles of low thermal conductivity 西索斯公司 2024-05-14 CN disclosed
CN-117736481-A Vinyl aromatic polymer particles containing treated anthracite particles 西索斯卓里第七公司 2024-03-22 CN disclosed
US-20240083817-A1 GEOPOLYMER COMPOSITE AND EXPANDABLE VINYL AROMATIC POLYMER GRANULATE AND EXPANDED VINYL AROMATIC POLYMER FOAM COMPRISING THE SAME SYNTHOS S.A. (PL) 2024-03-14 US disclosed
EP-2454313-B2 THERMO-INSULATING EXPANDED ARTICLES AND COMPOSITIONS FOR THE PREPARATION THEREOF VERSALIS SPA (IT) 2024-02-21 EP disclosed
US-11859066-B2 Use of a mineral having perovskite structure in vinyl aromatic polymer foam SYNTHOS S.A. (PL) 2024-01-02 US disclosed
CN-111094413-B Vinyl aromatic polymer particles and foams containing treated anthracite particles as athermanous additives and process for producing the same 西索斯卓里第七公司 2023-12-01 CN disclosed
EP-4219608-A1 VINYL AROMATIC POLYMER GRANULATE AND FOAM CONTAINING TREATED PARTICLES OF ANTHRACITE AS AN ATHERMANOUS ADDITIVE AND PROCESS FOR THE PRODUCTION THEREOF Synthos Dwory 7 spolka z ograniczona odpowiedzialnoscia (PL) 2023-08-02 EP disclosed
US-6812302-B2 CHARGING REACTION MIXTURE COMPRISING ALKYL ACRYLATE MONOMER AND INITIATOR INTO HEATED REACTOR; INITIATING POLYMERIZATION OF MONOMER WITH AROMATIC-CONTAINING INITIATOR TO PRODUCE POLYMER ROHM AND HAAS COMPANY 2004-11-02 US disclosed
US-6812313-B2 FOR IMPROVING FRACTURE TOUGHNESS OF CURED THERMOSET RESINS WHILE MAINTAINING DIMENSIONAL AND HEAT RESISTANCE; CRACK RESISTANCE; IMPACT STRENGTH; GLASS TRANSITION TEMPERATURE; FOR USE IN AEROSPACE/COMPUTERS ROHM AND HAAS COMPANY 2004-11-02 US disclosed
US-20030091602-A1 METHOD OF TREATING A COSMETIC COMPOSITION BY IRRADIATION WITH NIR RADIATION, AND ITS USE BASF AKTIENGESELLSCHAFT (DE) 2003-05-15 US disclosed
US-20030050397-A1 Thermoset compositions, tougheners, and composites thereof ROHM AND HAAS COMPANY 2003-03-13 US disclosed
US-20030022992-A1 Processes for preparing thermoset compositions and tougheners ROHM AND HAAS COMPANY 2003-01-30 US disclosed
EP-1270618-A2 Processes for preparing thermoset compositions and tougheners ROHM AND HAAS COMPANY (US) 2003-01-02 EP disclosed
CN-1307904-A Near infrared ray irradiation method for cosmetics and its application BASF AG (DE) 2001-08-15 CN disclosed
EP-1116484-A2 Treatment of a cosmetic with NIR-rays and its use BASF AKTIENGESELLSCHAFT (DE) 2001-07-18 EP disclosed
US-5580614-A MIXING SOLUTION OF CHELATED ORGANOMETALLIC COMPOUND HAVING POLYMERIZABLE LIGANDS WITH A HYDROLYZATE OF RADICALLY POLYMERIZED ALKOXYSILANES AND A PHOTOINITIATOR, THEN COATING A SUBSTRATE AND CURING WITH RADIATION FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1996-12-03 US disclosed
EP-0524417-A1 Coating composition and method for preparation of UV, UV/IR or IR/UV curable coatings FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1993-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030091602-A1 METHOD OF TREATING A COSMETIC COMPOSITION BY IRRADIATION WITH NIR RADIATION, AND ITS USE CUTA, TYR, ASAH2 RIPK1 4503/4885TRPA1 606/4885CACNA1F 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.