SCHEMBL10325880

SCHEMBL10325880

C=C(C)COC(=O)C1CC1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.41
ALDH1A1 P00352 1/20 0.41
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
HPGD P15428 2/20 0.38
RECQL P46063 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6351424 0.92 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2ATM
SCHEMBL6359904 0.90 ALDH1A1 (0.46) MAPTALDH1A1SMN1; SMN2HPGD
SCHEMBL28598650 0.87 GABRP (0.41) MAPTALDH1A1NPC1SMN1; SMN2HPGD
SCHEMBL27609193 0.82 MAPT (0.43) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3788658 0.82 ALOX15 (0.33) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3789516 0.81 PPM1B (0.36) MAPTALDH1A1NPC1L3MBTL1LMNA
SCHEMBL5685897 0.80 ALDH1A1 (0.36) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3792975 0.79 PPM1B (0.33) ALDH1A1SMN1; SMN2
SCHEMBL3784261 0.79 MIF (0.39) MAPTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL3289307 0.79 ATM (0.35) MAPTALDH1A1SMN1; SMN2HPGDATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012096117-A1 METHOD OF CONTROLLING HARMFUL ARTHROPOD, COMPOSITION, AND ELECTROSTATIC SPRAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-19 WO disclosed