Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10325880 | 0.87 | MAPT (0.41) | NPC1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL25845608 | 0.85 | GABRP (0.43) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL6351424 | 0.83 | ALDH1A1 (0.44) | TSHRALDH1A1SMN1; SMN2ATMCASP3 | |
| SCHEMBL6359904 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL18625010 | 0.79 | GABRA5 (0.50) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL670170 | 0.78 | GABRP (0.43) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL13601550 | 0.77 | KDM4E (0.44) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Ethyl Isonipecotate SCHEMBL27886 | 0.77 | MAPT (0.51) | GABRPGABRDGABRA1TSHRGABRB1 | |
| Ethyl Isonipecotate SCHEMBL6439825 | 0.77 | MAPT (0.51) | GABRPGABRDGABRA1TSHRGABRB1 | |
| SCHEMBL11559812 | 0.76 | TSHR (0.42) | GABRPGABRDGABRA1TSHRGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227103-A | Trisubstituted heteroaryl derivatives as SRC homologous-2 phosphatase inhibitors | 尼坎医疗公司 | 2021-08-06 | — | — | CN | disclosed |