Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515025 | 0.88 | MEN1 (0.55) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28023084 | 0.84 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12967186 | 0.82 | MEN1 (0.58) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5943019 | 0.79 | RAB9A (0.44) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22792257 | 0.77 | CASP3 (0.57) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19236921 | 0.77 | CASP3 (0.57) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21656855 | 0.76 | RARB (0.57) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL24570677 | 0.76 | MEN1 (0.58) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4380974 | 0.76 | MEN1 (0.63) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12967275 | 0.76 | KDM4E (0.54) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654880-B2 | Methods for preparation of glycosphingolipids and uses thereof | LIANG PI HUI (TW) | 2020-05-19 | — | — | US | disclosed |
| EP-2661440-B1 | METHOD FOR THE PREPARATION OF GLYCOSPHINGOLIPIDS | UNIV NAT TAIWAN (TW) | 2017-09-27 | — | — | EP | disclosed |
| US-20160229881-A1 | METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF | LIANG PI-HUI (TW) | 2016-08-11 | — | — | US | disclosed |
| US-20160229881-A1 | METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF | LIANG PI-HUI (TW) | 2016-08-11 | — | — | US | disclosed |
| US-9181292-B2 | Methods for preparation of glycosphingolipids and uses thereof | LIANG PI-HUI (TW) | 2015-11-10 | — | — | US | disclosed |
| US-9181292-B2 | Methods for preparation of glycosphingolipids and uses thereof | LIANG PI-HUI (TW) | 2015-11-10 | — | — | US | disclosed |
| US-20120178705-A1 | METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF | NATIONAL TAIWAN UNIVERSITY (TW) | 2012-07-12 | — | — | US | disclosed |
| US-20120178705-A1 | METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF | NATIONAL TAIWAN UNIVERSITY (TW) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178705-A1 | METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF | UGCG, CERS2, SGMS1 | L3MBTL1 1184/4885ALDH1A1 2865/4885MEN1 3181/4885 |
| US-20160229881-A1 | METHODS FOR PREPARATION OF GLYCOSPHINGOLIPIDS AND USES THEREOF | UGCG, CERS2, SGMS1 | L3MBTL1 1184/4885ALDH1A1 2865/4885MEN1 3181/4885 |
| US-10654880-B2 | Methods for preparation of glycosphingolipids and uses thereof | UGCG, CERS2, SGMS1 | L3MBTL1 1184/4885ALDH1A1 2865/4885MEN1 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.