Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31579716 | 0.83 | KDM4E (0.53) | RAB9AL3MBTL1SMN1; SMN2NPC1ACACB | |
| SCHEMBL18798976 | 0.81 | THRB (0.50) | RAB9AL3MBTL1MAPTSMN1; SMN2MAPK1 | |
| SCHEMBL1478065 | 0.81 | OPRM1 (0.42) | RAB9ANPC1ACACBKDM4ETHRB | |
| SCHEMBL28023084 | 0.79 | L3MBTL1 (0.49) | RAB9AL3MBTL1MAPTCASP3SENP8 | |
| SCHEMBL16216735 | 0.79 | KDM4E (0.50) | RAB9AL3MBTL1MAPTCASP3SENP8 | |
| SCHEMBL10327285 | 0.79 | L3MBTL1 (0.50) | RAB9AL3MBTL1MAPTCASP3SENP8 | |
| SCHEMBL21656510 | 0.79 | GRM2 (0.56) | RAB9AMAPTSMN1; SMN2NPC1NFKB1 | |
| SCHEMBL25355807 | 0.79 | THRB (0.42) | RAB9AL3MBTL1NPC1ACACBMEN1 | |
| SCHEMBL17050458 | 0.79 | RAB9A (0.49) | RAB9AL3MBTL1MAPTMAPK1NPC1 | |
| SCHEMBL31225434 | 0.78 | KDM4E (0.56) | RAB9AMAPTSMN1; SMN2NPC1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178400-A1 | Novel acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome | ABBOTT LABORATORIES | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178400-A1 | Novel acetyl-CoA carboxylase (ACC) inhibitors and their use in diabetes, obesity and metabolic syndrome | ACACA, ACACB, ACAT1 | RAB9A 3748/4885L3MBTL1 4006/4885MAPT 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.