Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14679074 | 0.91 | CA1 (0.68) | PRMT1KMT2AMEN1CA12CA1 | |
| SCHEMBL14679075 | 0.84 | PRMT1 (0.77) | PRMT1KMT2AMEN1CA12CA1 | |
| SCHEMBL126415 | 0.83 | PTPN1 (0.87) | PRMT1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3680148 | 0.83 | PRMT1 (0.75) | PRMT1KMT2AMEN1CA12CA1 | |
| SCHEMBL3107195 | 0.83 | PRMT1 (0.75) | PRMT1KMT2AMEN1CA12CA1 | |
| SCHEMBL8422583 | 0.83 | CA2 (1.00) | PRMT1KMT2AMEN1CA12CA1 | |
| SCHEMBL10327253 | 0.82 | PTGS1 (0.64) | PRMT1KMT2AMEN1CA12CA1 | |
| SCHEMBL14715824 | 0.81 | NPC1 (0.88) | PRMT1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL18103163 | 0.81 | NPC1 (0.88) | PRMT1KMT2AMEN1HPGDNPC1 | |
| SCHEMBL12010897 | 0.80 | KMT2A (0.91) | PRMT1KMT2AMEN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120178747-A9 | Compositions and methods for bone formation and remodeling | ENZO LIFE SCIENCES, INC. | 2012-07-12 | — | — | US | disclosed |
| US-20100298308-A1 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-4115059-A | BLEACHES, DETERGENTS | FMC CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298308-A1 | Compositions and methods for bone formation and remodeling | DKK1, BMP6, LRP6 | PRMT1 4518/4885KMT2A 4315/4885MEN1 2078/4885 |
| US-20120178747-A9 | Compositions and methods for bone formation and remodeling | DKK1, BMP6, LRP6 | PRMT1 4518/4885KMT2A 4315/4885MEN1 2078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.