Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488690 | 0.86 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10049719 | 0.80 | LMNA (0.39) | LMNAALDH1A1 | |
| SCHEMBL1143403 | 0.79 | ALDH1A1 (0.40) | LMNAALDH1A1 | |
| SCHEMBL16938750 | 0.79 | LMNA (0.32) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30420099 | 0.79 | ALDH1A1 (0.40) | LMNAALDH1A1 | |
| SCHEMBL33967 | 0.78 | CYP1A2 (0.32) | — | |
| SCHEMBL29400765 | 0.78 | CYP1A2 (0.32) | — | |
| SCHEMBL10205212 | 0.77 | LMNA (0.31) | LMNA | |
| Hydrochloric Acid SCHEMBL19858971 | 0.76 | CYP1A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3763676 | 0.76 | CYP1A2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1805966-B | Pyrimidine compounds having phosphonate groups as antiviral nucleotide analogs | INST OF ORGANIC CHENISTRY AND | 2013-03-13 | — | — | CN | disclosed |
| EP-1644389-B1 | PYRIMIDINE COMPOUNDS HAVING PHOSPHONATE GROUPS AS ANTIVIRAL NUCLEOTIDE ANALOGS | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 2011-01-19 | — | — | EP | disclosed |
| US-20060241081-A1 | Novel compounds and methods for therapy | INSTITUTE OF ORGANIC CHEMISTRY | 2006-10-26 | — | — | US | disclosed |
| US-7115592-B2 | Phosphonate substituted pyrimidine compounds and methods for therapy | INSTITUTE OF ORGANIC CHEMISTRY (CZ) | 2006-10-03 | — | — | US | disclosed |
| EP-1644389-A1 | PYRIMIDINE COMPOUNDS HAVING PHOSPHONATE GROUPS AS ANTIVIRAL NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2006-04-12 | — | — | EP | disclosed |
| US-20050075318-A1 | Novel compounds and methods for therapy | INSTITUTE OF ORGANIC CHENISTRY AND BIOCHEMISTRY ACADEMYOF SCIENCES OF THE CZECH REPUBLIC | 2005-04-07 | — | — | US | disclosed |
| WO-2004111064-A1 | PYRIMIDINE COMPOUNDS HAVING PHOSPHONATE GROUPS AS ANTIVIRAL NUCLEOTIDE ANALOGS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY, ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075318-A1 | Novel compounds and methods for therapy | ZC3HAV1, IFNAR1, EIF2AK2 | TKT 415/4885LMNA 2887/4885ALDH1A1 2417/4885 |
| US-20060241081-A1 | Novel compounds and methods for therapy | ZC3HAV1, IFNAR1, EIF2AK2 | TKT 415/4885LMNA 2887/4885ALDH1A1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.