Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30420099 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNATLR8TLR7 | |
| SCHEMBL2488690 | 0.86 | LMNA (0.36) | ALDH1A1KDM4ELMNACYP1A2HPGD | |
| SCHEMBL7919954 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4ELMNATLR8TLR7 | |
| SCHEMBL1032871 | 0.79 | TKT (0.33) | ALDH1A1LMNA | |
| SCHEMBL2494234 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNATLR8TLR7 | |
| SCHEMBL12368143 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNATLR8TLR7 | |
| SCHEMBL24309857 | 0.75 | PDE10A (0.35) | ALDH1A1KDM4ELMNACYP1A2PDE10A | |
| SCHEMBL10201389 | 0.75 | TLR8 (0.42) | ALDH1A1KDM4ELMNATLR8CYP1A2 | |
| SCHEMBL2396549 | 0.75 | LMNA (0.44) | ALDH1A1KDM4ELMNATLR8CYP1A2 | |
| SCHEMBL5748423 | 0.75 | TLR8 (0.42) | ALDH1A1KDM4ELMNATLR8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116376507-A | Ureido pyrimidinone modified polyethyleneimine adhesive and synthetic method thereof | 郑州大学 | 2023-07-04 | — | — | CN | claimed |
| CN-114716961-B | Self-complementary quadruple hydrogen bond supermolecule hot melt adhesive and synthesis method thereof | 郑州大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116103008-A | Strippable polyurethane hot melt adhesive based on reactive extrusion and synthesis method thereof | 郑州大学 | 2023-05-12 | — | — | CN | claimed |
| CN-114716961-A | Self-complementary quadruple hydrogen bond supramolecular hot melt adhesive and synthesis method thereof | 郑州大学 | 2022-07-08 | — | — | CN | claimed |
| US-11137242-B2 | Conductive fiber comprising metal nanobelt and carbon nanomaterial composite, method for producing conductive fiber, fibrous strain sensor, and method for producing fibrous strain sensor | KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE | 2021-10-05 | — | — | US | claimed |
| CN-108359227-B | Preparation method of reversible crosslinked hyperbranched polyester compound | 鲁东大学 | 2020-07-31 | — | — | CN | claimed |
| CN-108162528-B | Novel high-performance antibacterial antifogging film | 宿迁市金田塑业有限公司 | 2020-07-10 | — | — | CN | claimed |
| US-20190094005-A1 | CONDUCTIVE FIBER COMPRISING METAL NANOBELT AND CARBON NANOMATERIAL COMPOSITE, METHOD FOR PRODUCING CONDUCTIVE FIBER, FIBROUS STRAIN SENSOR, AND METHOD FOR PRODUCING FIBROUS STRAIN SENSOR | KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE | 2019-03-28 | — | — | US | claimed |
| US-10184059-B2 | Nanometal-nanocarbon hybrid material and method of manufacturing the same | KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE (KR) | 2019-01-22 | — | — | US | claimed |
| US-10100209-B2 | Work function-controlled carbon nanomaterial and metal nanowire hybrid transparent conductive film and method for manufacturing same | KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE (KR) | 2018-10-16 | — | — | US | claimed |
| CN-108359227-A | A kind of preparation method of reversible crosslink hyperbranched poly ester complexes | 鲁东大学 | 2018-08-03 | — | — | CN | claimed |
| US-20170073817-A1 | NANOMETAL-NANOCARBON HYBRID MATERIAL AND METHOD OF MANUFACTURING THE SAME | KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE | 2017-03-16 | — | — | US | claimed |
| US-20160222227-A1 | WORK FUNCTION-CONTROLLED CARBON NANOMATERIAL AND METAL NANOWIRE HYBRID TRANSPARENT CONDUCTIVE FILM AND METHOD FOR MANUFACTURING SAME | KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE | 2016-08-04 | — | — | US | claimed |
| CN-102993173-B | Preparation method of revaprzan hydrochloride | UNIV SHANDONG | 2014-09-03 | — | — | CN | claimed |
| CN-102993173-A | Preparation method of revaprzan hydrochloride | UNIV SHANDONG | 2013-03-27 | — | — | CN | claimed |
| US-11773067-B2 | (Trifluoromethyl)pyrimidine-2-amine compounds | ELI LILLY AND COMPANY (US) | 2023-10-03 | — | — | US | disclosed |
| CN-116376507-A | Ureido pyrimidinone modified polyethyleneimine adhesive and synthetic method thereof | 郑州大学 | 2023-07-04 | — | — | CN | disclosed |
| EP-0901474-A1 | ARYL PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| US-5863924-A | Aryl pyrimidine derivatives | SYNTEX (U.S.A.) INC. (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1997044326-A1 | ARYL PYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773067-B2 | (Trifluoromethyl)pyrimidine-2-amine compounds | P2RX1, P2RX2, P2RY1 | ALDH1A1 276/4885KDM4E 1718/4885LMNA 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.