SCHEMBL10329461

SCHEMBL10329461

Cc1cc(S)nc(S)c1C#N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.46
RECQL P46063 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALDH1A1 P00352 8/20 0.39
HPGD P15428 4/20 0.39
HSD17B10 Q99714 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 3/20 0.37
ALOX15 P16050 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
HAVCR2 Q8TDQ0 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
POLB P06746 3/20 0.36
XBP1 P17861 2/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3985050 0.83 KDM4E (0.60) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL17782879 0.80 KDM4E (0.52) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL20642444 0.74 PKM (0.46) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL1320853 0.73 L3MBTL1 (0.68) KDM4EMEN1KMT2ATDP1ALDH1A1
SCHEMBL4657588 0.73 KDM4E (0.41) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL4658289 0.71 KCNH2 (0.38) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL1721807 0.67 PSMD14 (0.40) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL13979542 0.66 KMT2A (0.50) KDM4ERECQLMEN1KMT2ATDP1
SCHEMBL21048258 0.65 KDM4E (0.34) KDM4EMEN1KMT2AALDH1A1HPGD
SCHEMBL3174550 0.65 HTT (0.36) KDM4EMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329387-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-11 US disclosed
US-8329387-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-12-11 US disclosed
EP-2300518-B1 ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA (US) 2012-08-15 EP disclosed
US-8221965-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-07-17 US disclosed
US-8221965-B2 Antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-07-17 US disclosed
WO-2010004378-A1 ANTIRELECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-01-14 WO disclosed
US-20100009293-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
US-20100009293-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
US-20100009297-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
US-20100009297-A1 Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2010-01-14 US disclosed
WO-2010004377-A1 ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-01-14 WO disclosed