Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559919 | 0.78 | ALDH1A1 (0.40) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL30751791 | 0.78 | ALDH1A1 (0.40) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL6060756 | 0.77 | LRRK2 (0.33) | ALDH1A1HPGDSMN1; SMN2GAAKDM4E | |
| SCHEMBL15691383 | 0.77 | ALDH1A1 (0.39) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL6569026 | 0.75 | ALDH1A1 (0.41) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL3828718 | 0.75 | ALDH1A1 (0.44) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL16539264 | 0.75 | ALDH1A1 (0.38) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL677194 | 0.75 | L3MBTL1 (0.45) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL1261198 | 0.75 | NOS2 (0.54) | RECQLALDH1A1NPC1LMNAPOLB | |
| SCHEMBL27158634 | 0.75 | SMN1; SMN2 (0.40) | RECQLALDH1A1NPC1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156599-A1 | SYNTHESIS OF BRUTON'S TYROSINE KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-24 | — | — | WO | disclosed |
| EP-2406226-B1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | GRUENENTHAL GMBH (DE) | 2015-09-16 | — | — | EP | disclosed |
| US-8586755-B2 | Substituted nicotinamides as KCNQ2/3 modulators | Grünenthal GmbH (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20120184550-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | GRUNENTHAL GMBH (DE) | 2012-07-19 | — | — | US | disclosed |
| US-8178684-B2 | Substituted nicotinamides as KCNQ2/3 modulators | GRUENENTHAL GMBH (DE) | 2012-05-15 | — | — | US | disclosed |
| EP-2406226-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | Grünenthal GmbH (DE) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010102809-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | Grünenthal GmbH (DE) | 2010-09-16 | — | — | WO | disclosed |
| US-20100234429-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | Grünenthal GmbH (DE) | 2010-09-16 | — | — | US | disclosed |
| EP-1940849-B1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-1915344-B1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080207447-A1 | Cyanopyridine Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1940849-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1915344-A1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007045588-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007014913-A1 | CYANOPYRIDINE PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | IPO5, PIR, ACHE | PSMD14 2941/4885COPS5 1932/4885RECQL 2927/4885 |
| US-20120184550-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | KCNQ2, KCNQ1, KCNQ3 | PSMD14 3852/4885COPS5 4653/4885RECQL 554/4885 |
| US-20080207447-A1 | Cyanopyridine Pesticides | CBR3, CBR1, CHRM1 | PSMD14 3814/4885COPS5 1603/4885RECQL 2037/4885 |
| US-20100234429-A1 | SUBSTITUTED NICOTINAMIDES AS KCNQ2/3 MODULATORS | KCNQ1, KCNQ2, KCNQ3 | PSMD14 2756/4885COPS5 4518/4885RECQL 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.