SCHEMBL8576325

SCHEMBL8576325

COC(=O)CC(S)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
HSD17B10 Q99714 1/20 0.44
MGAM O43451 2/20 0.39
GAA P10253 2/20 0.39
SI P14410 2/20 0.39
MGAM2 Q2M2H8 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
MMP1 P03956 1/20 0.37
MMP13 P45452 1/20 0.37
KMT2A Q03164 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
TP53 P04637 1/20 0.32
TET2 Q6N021 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 1/20 0.32
ZDHHC7 Q9NXF8 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29926745 1.00 TSHR (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL16320589 0.81 ALDH1A1 (0.40) TSHRHSD17B10MGAMGAASI
SCHEMBL10802315 0.81 TDP1 (0.40) TSHRHSD17B10SMN1; SMN2MMP1MMP13
SCHEMBL16341023 0.77 TDP1 (0.38) TSHRHSD17B10MGAMGAASI
SCHEMBL7784845 0.77 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL10329464 0.77 TSHR (0.41) TSHRHSD17B10MGAMGAASI
SCHEMBL7784843 0.77 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL14239656 0.77 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL10329465 0.77 SMN1; SMN2 (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL15362779 0.76 NAAA (0.50) TSHRMAPTZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107987513-A A kind of endurance polyurethane material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-05-04 CN claimed
CN-107903615-A A kind of composite modified polyurethane material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-04-13 CN claimed
CN-107903592-A A kind of high temperature resistant polyethylene terephthalate composite material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-04-13 CN claimed
CN-107760011-A A kind of modified polyurethane material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-03-06 CN claimed
CN-107759966-A A kind of anti-stress cracking polyformaldehyde material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-03-06 CN claimed
EP-0289909-B1 ALL AQUEOUS FORMULATIONS OF ORGANO-PHOSPHOROUS PESTICIDES BASF Corporation (US) 1992-09-16 EP claimed
US-4851217-A All aqueous formulations of organo-phosphorous pesticides BASF CORPORATION (US) 1989-07-25 US claimed
EP-0289909-A2 All aqueous formulations of organo-phosphorous pesticides BASF Corporation (US) 1988-11-09 EP claimed
CN-114315896-B 2- (diphenyl thiophosphoryl) succinate and synthetic method and application thereof 湖北大学 2023-06-23 CN disclosed
CN-114315896-A 2- (diphenyl thiophosphoryl) succinate and synthesis method and application thereof 湖北大学 2022-04-12 CN disclosed
WO-2020045454-A1 RUBBER COMPOSITION, METAL-RUBBER COMPOSITE MOLDED BODY AND METHOD FOR PRODUCING METAL-RUBBER COMPOSITE MOLDED BODY 住友化学株式会社 2020-03-05 WO disclosed
CN-107987513-A A kind of endurance polyurethane material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-05-04 CN disclosed
CN-107903592-A A kind of high temperature resistant polyethylene terephthalate composite material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-04-13 CN disclosed
CN-107903615-A A kind of composite modified polyurethane material and preparation method thereof 四川力智久创知识产权运营有限公司 2018-04-13 CN disclosed
WO-1994000120-A1 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1994-01-06 WO disclosed
EP-0234129-B1 BONDED PHASE OF SILICA FOR SOLID PHASE EXTRACTION J.T. BAKER INC. (US) 1991-02-20 EP disclosed
US-4701492-A ANCHORING TO SILICA REINFORCEMENT; TIRES RHONE-POULENC CHIMIE DE BASE (FR) 1987-10-20 US disclosed
EP-0234129-A2 Bonded phase of silica for solid phase extraction J.T. BAKER INC. (US) 1987-09-02 EP disclosed
US-4680121-A Bonded phase of silica for solid phase extraction J. T. BAKER CHEMICAL COMPANY (US) 1987-07-14 US disclosed
US-4650784-A Bonded phase of silica for solid phase extraction J. T. BAKER CHEMICAL COMPANY (US) 1987-03-17 US disclosed