Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330434 | 0.89 | CHEK1 (0.45) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL10330427 | 0.85 | CHEK1 (0.50) | MAPTSMN1; SMN2HSP90AA1MEN1KMT2A | |
| SCHEMBL10330432 | 0.81 | CHEK1 (0.47) | MAPTSMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL10330429 | 0.73 | CHEK1 (0.45) | RAB9ASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19821674 | 0.72 | HSP90AA1 (0.45) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL19821675 | 0.72 | HSP90AA1 (0.43) | MAPTTSHRHSP90AA1MEN1KMT2A | |
| SCHEMBL19827143 | 0.71 | CHEK1 (0.42) | MAPTNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL14773924 | 0.70 | ME2 (0.74) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL19827140 | 0.69 | MEN1 (0.42) | MAPTSMN1; SMN2TSHRHSP90AA1MEN1 | |
| SCHEMBL10330395 | 0.69 | ALDH1A1 (0.42) | MAPTSMN1; SMN2TSHRHSP90AA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222429-B2 | Photodissociable protective group | National University Corporation NARA Institute of Science and Technology (JP) | 2012-07-17 | — | — | US | disclosed |
| US-8222429-B2 | Photodissociable protective group | National University Corporation NARA Institute of Science and Technology (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110028738-A1 | PHOTODISSOCIABLE PROTECTIVE GROUP | National University Corporation NARA Institute of Science and Technology (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028738-A1 | PHOTODISSOCIABLE PROTECTIVE GROUP | National University Corporation NARA Institute of Science and Technology (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028738-A1 | PHOTODISSOCIABLE PROTECTIVE GROUP | CRY2, CRY1, APEX1 | MAPT 4249/4885NPC1 4455/4885TP53 4246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.