Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839344 | 0.86 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL16607366 | 0.86 | MEN1 (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10382093 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7797419 | 0.83 | GSK3B (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL12120089 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10943385 | 0.81 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17532246 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10852328 | 0.80 | THRA (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL16607367 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11855822 | 0.80 | NAAA (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222402-B2 | Preparation process | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-17 | — | — | US | disclosed |
| US-8222402-B2 | Preparation process | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-07-17 | — | — | US | disclosed |
| US-20110071286-A1 | NOVEL PREPARATION PROCESS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| US-20110071286-A1 | NOVEL PREPARATION PROCESS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-03-24 | — | — | US | disclosed |
| WO-2009021942-A1 | NOVEL PREPARATION PROCESS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071286-A1 | NOVEL PREPARATION PROCESS | RPLP1, RPLP2, CYP1B1 | MEN1 353/4885KMT2A 4390/4885ALDH1A1 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.