Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.54 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ILK | Q13418 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090637 | 0.88 | NCF1 (0.47) | PDE3BPDE3ANCF1KDM4EALDH1A1 | |
| SCHEMBL10333403 | 0.78 | PDE3B (0.51) | PDE3BPDE3AKDM4EALDH1A1POLB | |
| SCHEMBL10334229 | 0.76 | PDE3B (0.50) | PDE3BPDE3AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7257484 | 0.75 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2ILKMEN1 | |
| SCHEMBL10333619 | 0.74 | GAA (0.57) | PDE3BPDE3APDE2AKDM4EALDH1A1 | |
| SCHEMBL4865999 | 0.74 | NCF1 (0.61) | PDE3BPDE3ANCF1PDE2AKDM4E | |
| SCHEMBL10334199 | 0.72 | NCF1 (0.47) | PDE3BPDE3ANCF1KDM4EALDH1A1 | |
| SCHEMBL25366182 | 0.72 | GAA (0.58) | PDE3BPDE3AKDM4EALDH1A1POLB | |
| SCHEMBL17942624 | 0.72 | KDM4E (0.60) | PDE3BPDE3ANCF1PDE2AKDM4E | |
| SCHEMBL31414248 | 0.72 | KDM4E (0.63) | PDE3BPDE3ANCF1PDE2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | claimed |
| US-4921950-A | Preparation of 3'azido-3-'-deoxythymidine | BURROUGHS WELLCOME CO. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | disclosed |