Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090637 | 0.78 | NCF1 (0.47) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL10333750 | 0.78 | PDE3B (0.54) | PDE3BPDE3AKDM4EALDH1A1LMNA | |
| SCHEMBL25366182 | 0.78 | GAA (0.58) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL30588978 | 0.78 | GAA (0.58) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL10333544 | 0.77 | PDE3B (0.57) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL17942820 | 0.70 | ALDH1A1 (0.50) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL9755422 | 0.70 | NQO2 (0.60) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL10333619 | 0.69 | GAA (0.57) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL10334229 | 0.69 | PDE3B (0.50) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL12467975 | 0.69 | PDPK1 (0.34) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | claimed |
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | disclosed |