Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 5/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090637 | 0.84 | NCF1 (0.47) | NCF1TYMSPDE3BPDE3AALDH1A1 | |
| SCHEMBL10333628 | 0.73 | ILK (0.42) | TYMSPDE3BPDE3AALDH1A1KMT2A | |
| SCHEMBL11963370 | 0.73 | TTK (0.52) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL11752456 | 0.73 | TTK (0.64) | ALDH1A1TSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL10333750 | 0.72 | PDE3B (0.54) | NCF1TYMSPDE3BPDE3AALDH1A1 | |
| SCHEMBL23452966 | 0.72 | NCF1 (0.74) | NCF1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL10333619 | 0.71 | GAA (0.57) | PDE3BPDE3AALDH1A1CYP3A4KMT2A | |
| SCHEMBL30185818 | 0.70 | ALDH1A1 (0.56) | NCF1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL25366182 | 0.69 | GAA (0.58) | PDE3BPDE3AALDH1A1TP53CYP3A4 | |
| SCHEMBL10333403 | 0.69 | PDE3B (0.51) | PDE3BPDE3AALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | disclosed |