Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333628 | 0.87 | ILK (0.42) | PDE3BPDE3APLAUALDH1A1HPGD | |
| SCHEMBL10333619 | 0.77 | GAA (0.57) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL10333750 | 0.76 | PDE3B (0.54) | PDE3BPDE3AALDH1A1KDM4EILK | |
| SCHEMBL25366182 | 0.72 | GAA (0.58) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL30588978 | 0.72 | GAA (0.58) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL7256571 | 0.72 | GSK3A (0.58) | RPS6KA3CDK2GSK3AGSK3BCYP3A4 | |
| SCHEMBL7256564 | 0.69 | GSK3A (0.58) | RPS6KA3CDK2GSK3AGSK3BCYP3A4 | |
| SCHEMBL10333403 | 0.69 | PDE3B (0.51) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL3044443 | 0.69 | ESR2 (0.54) | PDE3BPDE3APLAUALDH1A1HPGD | |
| SCHEMBL9406881 | 0.68 | POLB (0.66) | PDE3BPDE3APLAUALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | disclosed |