SCHEMBL10334303

SCHEMBL10334303

COc1ccc(OC(=O)COC(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.51
LMNA P02545 1/20 0.51
TDP1 Q9NUW8 4/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
ATM Q13315 1/20 0.47
ACP3 P15309 1/20 0.46
KLK7 P49862 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
EPHX1 P07099 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9292224 0.89 ADRA1A (0.48) LMNAL3MBTL1ATMALDH1A1HTT
SCHEMBL10335682 0.88 ALDH1A1 (0.54) GAALMNATDP1L3MBTL1ALDH1A1
SCHEMBL10334901 0.87 LMNA (0.50) GAALMNATDP1L3MBTL1NPC1
SCHEMBL10335664 0.85 IDO1 (0.44) LMNATDP1ALDH1A1KMT2ATAAR1
SCHEMBL10335591 0.83 HTR1A (0.54) LMNATDP1L3MBTL1ATMALDH1A1
SCHEMBL10334683 0.83 ATM (0.56) TDP1L3MBTL1ATMKLK7ALDH1A1
SCHEMBL9292603 0.81 MEN1 (0.45) L3MBTL1ALDH1A1HTTSMN1; SMN2KMT2A
SCHEMBL166151 0.80 ALDH1A1 (0.51) LMNAL3MBTL1ALDH1A1HTTSMN1; SMN2
SCHEMBL10334717 0.80 PTPN7 (0.54) GAALMNAALDH1A1SMN1; SMN2KMT2A
SCHEMBL10334917 0.79 LMNA (0.51) GAALMNATDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4964893-A REDUCING INJURY TO A CROP PLANT MONSANTO COMPANY (US) 1990-10-23 US disclosed