SCHEMBL10336019

SCHEMBL10336019

CC(C)(C)C(O)Cn1cccc1

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
SLC5A2 P31639 2/20 0.37
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10928479 0.73 FDPS (0.49)
SCHEMBL7991895 0.72
SCHEMBL6627458 0.68 SLC18A3 (0.37) TSHRKDM4E
SCHEMBL28124381 0.67 KDM4E (0.30) KDM4E
SCHEMBL7289612 0.67 ALDH1A1 (0.33)
SCHEMBL218490 0.66 TP53 (0.31)
SCHEMBL7126010 0.65 KDM4E (0.31) KDM4E
SCHEMBL3971520 0.65 KMT2A (0.47) TSHRSLC5A2KDM4E
SCHEMBL7148428 0.65 MAPT (0.41)
SCHEMBL11252840 0.64 CYP19A1 (0.45) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4968712-A PHYTOPATHOGENS, AGRICULTURE BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0007505-B1 ALPHA-AZOLYL-BETA-HYDROXY-KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1981-09-30 EP disclosed