Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603996 | 0.97 | ALDH1A1 (0.41) | ALDH1A1TDP1KDM4EMAPTPOLB | |
| Nitric Acid SCHEMBL23493543 | 0.92 | CA5A (0.42) | ALDH1A1TDP1KDM4EMAPTPOLB | |
| Nitric Acid SCHEMBL28232131 | 0.92 | CA5A (0.42) | ALDH1A1TDP1KDM4EMAPTPOLB | |
| SCHEMBL10337286 | 0.86 | ALDH1A1 (0.38) | ALDH1A1TDP1KDM4EMAPTPOLB | |
| SCHEMBL2349341 | 0.85 | ALDH1A1 (0.33) | ALDH1A1TDP1KDM4EALOX15 | |
| SCHEMBL11653734 | 0.79 | LMNA (0.33) | ALDH1A1TDP1KDM4E | |
| SCHEMBL10337185 | 0.73 | — | — | |
| SCHEMBL31344499 | 0.72 | LMNA (0.46) | ALDH1A1KDM4EMAPT | |
| SCHEMBL513918 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2 | |
| Trolamine SCHEMBL2396169 | 0.69 | CA5A (0.47) | ALDH1A1TDP1KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H786-H | COPOLYFORMALS OF 1,2-BIS(2-HYDROXYETHYL)-1,2-DICARBADODECABORANE AND POLYNITROALKYL DIOLS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1990-06-05 | — | — | US | disclosed |
| US-H784-H | COPOLYFORMALS OF 1,2-BIS(2-HYDROXYETHYL)-1,2-DICARBADODECABORANE(12) AND POLYFLUOROALKYL DIOLS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1990-06-05 | — | — | US | disclosed |
| US-H730-H | Hydroxy-terminated copolyformals of fluorodiols with nitrodiols | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1990-02-06 | — | — | US | disclosed |