Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78097 | 0.81 | TSHR (0.50) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL929945 | 0.79 | CYP3A4 (0.56) | TSHRCASP1PTGS1CYP3A4ALDH1A1 | |
| SCHEMBL8486745 | 0.76 | KMT2A (0.51) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL14660398 | 0.76 | TSHR (0.45) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL923019 | 0.74 | TP53 (0.46) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL4237202 | 0.74 | TRPA1 (0.50) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL28074392 | 0.74 | TSHR (0.43) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL14925306 | 0.74 | TRIM24 (0.44) | TSHRCASP1ACHETRPA1PTGS1 | |
| SCHEMBL4229019 | 0.74 | LTA4H (0.53) | TSHRCASP1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL14707162 | 0.74 | MEN1 (0.47) | TSHRCASP1ACHETRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387554-A2 | Liquid epoxy polymer composition and use thereof | International Business Machines Corporation (US) | 1990-09-19 | — | — | EP | disclosed |
| EP-0375980-A2 | Epoxy composition of increased thermal conductivity and use thereof | International Business Machines Corporation (US) | 1990-07-04 | — | — | EP | disclosed |