SCHEMBL929945

SCHEMBL929945

COc1ccc(C)c(O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.56
NPC1 O15118 3/20 0.55
RAB9A P51151 2/20 0.55
ALDH1A1 P00352 3/20 0.53
MAPK1 P28482 3/20 0.53
HPGD P15428 3/20 0.53
TRIM24 O15164 1/20 0.53
TYR P14679 1/20 0.53
TRIM33 Q9UPN9 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
THRB P10828 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
KMT2A Q03164 1/20 0.52
MCL1 Q07820 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16230595 0.85 NPC1 (0.46) CYP3A4NPC1RAB9AALDH1A1MAPK1
Methacrylic Acid SCHEMBL29724204 0.84 HPGD (0.53) CYP3A4NPC1RAB9AALDH1A1MAPK1
SCHEMBL78097 0.83 TSHR (0.50) CYP3A4ALDH1A1MAPK1HPGDKDM4E
SCHEMBL5153274 0.83 ESR2 (0.57) NPC1RAB9AMAPK1SMN1; SMN2MEN1
SCHEMBL172689 0.81 ALDH1A1 (0.57) CYP3A4NPC1RAB9AALDH1A1MAPK1
SCHEMBL67498 0.80 ALDH1A1 (0.61) CYP3A4NPC1RAB9AALDH1A1MAPK1
SCHEMBL340086 0.80 NPC1 (0.60) CYP3A4NPC1RAB9AALDH1A1MAPK1
SCHEMBL29950410 0.80 ALDH1A1 (0.61) CYP3A4NPC1RAB9AALDH1A1MAPK1
SCHEMBL10337273 0.79 TSHR (0.46) CYP3A4NPC1RAB9AALDH1A1MAPK1
SCHEMBL22313516 0.79 CYP1A2 (0.52) CYP3A4NPC1RAB9AALDH1A1TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250290009-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2025-09-18 US claimed
EP-4522714-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING Firmenich SA (CH) 2025-03-19 EP claimed
CN-118055753-A Composition comprising an oxidation dye and an amine salt 花王株式会社 2024-05-17 CN claimed
WO-2023217712-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2023-11-16 WO claimed
CN-114146071-B Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2023-02-28 CN claimed
CN-114146071-A Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome 西北农林科技大学深圳研究院 2022-03-08 CN claimed
CN-105017249-B A kind of preparation method of the hydazone derivative of 1,2,4-triazole [4,3-α] pyridine ring 浙江工业大学 2016-11-23 CN claimed
CN-104892602-A Hydrazone derivative containing 1,2,4-triazole [4,3-a] pyridine ring as well as preparation and application of hydrazone derivative UNIV ZHEJIANG TECHNOLOGY 2015-09-09 CN claimed
CN-120737529-A Marine polyethylene insulated cable material and preparation method thereof 扬州光明电缆有限公司 2025-10-03 CN disclosed
EP-3947365-B1 SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF BIONOMICS LTD (AU) 2025-10-01 EP disclosed
US-20250290009-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING FIRMENICH SA (CH) 2025-09-18 US disclosed
EP-4522714-A1 NEW LOW SULFUR TERPENE MIX RECOVERY FROM WOOD PROCESSING Firmenich SA (CH) 2025-03-19 EP disclosed
US-12139473-B2 Substituted-N-heteroaryl compounds and uses thereof BIONOMICS LIMITED (AU) 2024-11-12 US disclosed
US-12090146-B2 Substituted-pyridinyl compounds and uses thereof BIONOMICS LIMITED (AU) 2024-09-17 US disclosed
US-4061642-A AZO DYE INTERMEDIATES CASSELLA FARBWERKE MAINKUR AG (DT) 1977-12-06 US disclosed
US-3980659-A INSECTICIDES, INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed
US-3956294-A AZO DYES, PESTICIDES, ANALEPTICS, ANALGESICS, DIURETICS CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3954782-A 2,6-Hydrazino-3-pyridine carboxyamides CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3947463-A Certain 2-amino-nicotinonitrile derivatives CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-30 US disclosed
US-3946024-A INTERMEDIATES FOR AZO DYES CASSELLA FARBWERKE MAINKUR AG (DT) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12090146-B2 Substituted-pyridinyl compounds and uses thereof GABRE, GAP43, GRIN2A CYP3A4 1194/4885NPC1 4607/4885RAB9A 2860/4885
US-12139473-B2 Substituted-N-heteroaryl compounds and uses thereof SCN3A, KCND3, GRIN3A CYP3A4 2075/4885NPC1 2406/4885RAB9A 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.