SCHEMBL4237202

SCHEMBL4237202

Cc1ccc(OC(C)C)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.50
PTGS1 P23219 1/20 0.50
CACNA1C Q13936 1/20 0.50
ALDH1A1 P00352 3/20 0.48
TDP1 Q9NUW8 1/20 0.47
KMT2A Q03164 1/20 0.47
PARP10 Q53GL7 1/20 0.46
MAPT P10636 1/20 0.44
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
HPGD P15428 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
POLB P06746 1/20 0.43
GLA P06280 1/20 0.42
ACHE P22303 1/20 0.41
BRD4 O60885 1/20 0.41
BRPF1 P55201 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3720563 0.83 ALDH1A1 (0.48) ALDH1A1TDP1KMT2APARP10MAPT
SCHEMBL1052924 0.83 ALDH1A1 (0.52) ALDH1A1KMT2APARP10KDM4EPOLB
SCHEMBL339527 0.83 ALDH1A1 (0.52) ALDH1A1KMT2APARP10MAPTHPGD
SCHEMBL15599154 0.81 TDP1 (0.74) TRPA1PTGS1CACNA1CALDH1A1TDP1
SCHEMBL13220460 0.81 TDP1 (0.54) TRPA1PTGS1CACNA1CALDH1A1TDP1
SCHEMBL10153872 0.80 TDP1 (0.62) ALDH1A1TDP1KMT2APARP10MAPT
SCHEMBL4962026 0.79 ALDH1A1 (0.48) ALDH1A1KMT2APARP10HPGDPOLB
SCHEMBL13211785 0.78 ALDH2 (0.55) TRPA1PTGS1CACNA1CALDH1A1TDP1
SCHEMBL78097 0.78 TSHR (0.50) TRPA1PTGS1CACNA1CALDH1A1KMT2A
SCHEMBL8208073 0.78 ALDH1A1 (0.47) ALDH1A1KMT2APARP10HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118666647-A Green co-production method of benzoquinone compound and hydroquinone 浙江大学 2024-09-20 CN claimed
CN-118666647-A Green co-production method of benzoquinone compound and hydroquinone 浙江大学 2024-09-20 CN disclosed
EP-3468541-B1 ANTIPROTOZOAL AGENTS UNIV KIEL CHRISTIAN ALBRECHTS (DE) 2021-09-22 EP disclosed
WO-2017211988-A1 ACTIVE AGENTS AGAINST PROTOZOA CHRISTIAN-ALBRECHTS-UNIVERSITÄT ZU KIEL (DE) 2017-12-14 WO disclosed
US-20090209522-A1 Heterocyclic Non-Peptide GNRH Antagonists TAKEDA CAMBRIDGE LIMITED (GB) 2009-08-20 US disclosed
EP-1896465-A1 HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS Takeda Cambridge Limited (GB) 2008-03-12 EP disclosed
WO-2007000582-A1 HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS TAKEDA CAMBRIDGE LIMITED (GB) 2007-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209522-A1 Heterocyclic Non-Peptide GNRH Antagonists GNRHR, GHRHR, FSHR TRPA1 3428/4885PTGS1 2635/4885CACNA1C 3084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.