Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490289 | 0.92 | GABRA1 (0.45) | GABRA1GABRB2HMGB1CXCL12LMNA | |
| SCHEMBL8772297 | 0.92 | HMGB1 (0.58) | GABRA1GABRB2HMGB1CXCL12LMNA | |
| SCHEMBL10337549 | 0.88 | HMGB1 (0.42) | GABRA1GABRB2HMGB1CXCL12KDM4E | |
| SCHEMBL5681182 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2HMGB1CXCL12LMNA | |
| SCHEMBL29525444 | 0.85 | LMNA (0.55) | GABRA1GABRB2LMNAHTTKDM4E | |
| SCHEMBL22778226 | 0.85 | LMNA (0.55) | GABRA1GABRB2LMNAHTTKDM4E | |
| SCHEMBL15342325 | 0.83 | LMNA (0.48) | GABRA1GABRB2LMNAHTTPKM | |
| SCHEMBL8962592 | 0.82 | KEAP1 (0.47) | HMGB1CXCL12 | |
| SCHEMBL29083860 | 0.82 | BCL2 (0.50) | HMGB1CXCL12KDM4EPOLBMCL1 | |
| SCHEMBL11755073 | 0.82 | CYP2C19 (0.46) | GABRA1GABRB2HMGB1CXCL12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4896723-A | PHENOLIC RESIN CROSSLINKING | MOBIL OIL CORPORATION (US) | 1990-01-30 | — | — | US | disclosed |
| US-4859717-A | Cross-linked polyvinyl alcohols and oil reservoir permeability control therewith | MOBIL OIL CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |