SCHEMBL8772297

SCHEMBL8772297

CCc1cc(Cc2cc(CC)c(O)c3ccccc23)c2ccccc2c1O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.58
CXCL12 P48061 1/20 0.58
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NSD2 O96028 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337449 0.92 GABRA1 (0.48) HMGB1CXCL12GABRA1GABRB2LMNA
SCHEMBL12302946 0.88
SCHEMBL9490289 0.88 GABRA1 (0.45) HMGB1CXCL12GABRA1GABRB2LMNA
SCHEMBL8962592 0.86 KEAP1 (0.47) HMGB1CXCL12
SCHEMBL8962652 0.85 HMGB1 (0.44) HMGB1CXCL12
SCHEMBL10337549 0.85 HMGB1 (0.42) HMGB1CXCL12GABRA1GABRB2KDM4E
SCHEMBL29525444 0.82 LMNA (0.55) GABRA1GABRB2LMNAHTTKDM4E
SCHEMBL22778226 0.82 LMNA (0.55) GABRA1GABRB2LMNAHTTKDM4E
SCHEMBL8772369 0.81 HSPA5 (0.49) HMGB1CXCL12LMNAKDM4EMEN1
SCHEMBL15342325 0.80 LMNA (0.48) GABRA1GABRB2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
US-5543286-A CONTAINING AN ORGANIC SILVER SALT AND A PYRROLE COMPOUND;HIGH CONTRAST IMAGES CANON KABUSHIKI KAISHA (JP) 1996-08-06 US disclosed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5409798-A Base layer containing polymerizable compound, photosensitive layer capable of peeling development containing different polymerizable compound, layer-forming polymer, photoinitiator, peeling support layer CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0530674-A1 Plate blank, process for producing printing plate from plate blank, and printing method and apparatus using plate CANON KABUSHIKI KAISHA (JP) 1993-03-10 EP disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0505155-A1 Heat-developable masking layer CANON KABUSHIKI KAISHA (JP) 1992-09-23 EP disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 EP disclosed