Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MB | P02144 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368269 | 1.00 | RAB9A (0.58) | RAB9ANPC1TSHRHPGDMEN1 | |
| SCHEMBL30675577 | 0.84 | PKM (0.59) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL13414534 | 0.84 | ALDH1A1 (0.53) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL405478 | 0.84 | ALDH1A1 (0.57) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL11802375 | 0.84 | PKM (0.59) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL30421453 | 0.84 | NPC1 (0.62) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL8251619 | 0.84 | NPC1 (0.62) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL9234372 | 0.84 | SMN1; SMN2 (0.60) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL1136776 | 0.84 | PKM (0.54) | RAB9ANPC1TSHRMEN1KMT2A | |
| SCHEMBL147440 | 0.82 | IDO1 (0.65) | RAB9ANPC1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651643-A4 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM LLC (BM) | 2008-10-08 | — | — | EP | claimed |
| US-20070259852-A1 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM LLC | 2007-11-08 | — | — | US | claimed |
| US-7253164-B2 | Bicyclic compounds and compositions as PDF inhibitors | IRM LLC (BM) | 2007-08-07 | — | — | US | claimed |
| EP-1651643-A2 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM, LLC (BM) | 2006-05-03 | — | — | EP | claimed |
| US-20050197326-A1 | Bicyclic compounds and compostions as PDF inhibitors | IRM LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005011611-A2 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | IRM, LLC (BM) | 2005-02-10 | — | — | WO | claimed |
| WO-2025090871-A1 | ELECTROPHILIC PURINE COMPOUNDS FOR MODIFICATION OF PROTEINS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-05-01 | — | — | WO | disclosed |
| EP-3356345-B1 | HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS | MAX PLANCK GESELLSCHAFT (DE) | 2023-11-08 | — | — | EP | disclosed |
| EP-3466946-B1 | THIOPHENE, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL APPLICATION OF SAME | DONGBAO PURPLE STAR HANGZHOU BIOPHARMACEUTICAL CO LTD (CN) | 2023-08-30 | — | — | EP | disclosed |
| WO-2023158862-A2 | STIMULATOR OF INTERFERON GENES (STING) MODULATORS, AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| EP-3837732-A1 | NOVEL CATALYTIC MATERIALS | University of Tartu (EE) | 2021-06-23 | — | — | EP | disclosed |
| US-10829483-B2 | Thiophene, manufacturing method thereof, and pharmaceutical application of same | CSTONE PHARMACEUTICAL (SUZHOU) CO., LTD. (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200140423-A1 | Thiophene, Manufacturing Method Thereof, And Pharmaceutical Application Of Same | DONGBAO PURPLE STAR (HANGZHOU) BIOPHARMACEUTICAL CO., LTD (CN) | 2020-05-07 | — | — | US | disclosed |
| EP-0230946-A2 | Process for the preparation of quinolonecarboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0230947-A1 | Halogenobenzoic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0230948-A2 | Benzoylacetic acid ester derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0029658-A1 | Salts of dihalo-2-quinoxaline carboxylic acids, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4252954-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197326-A1 | Bicyclic compounds and compostions as PDF inhibitors | PDF, FDPS, DCTPP1 | RAB9A 2389/4885NPC1 1383/4885TSHR 4619/4885 |
| US-10829483-B2 | Thiophene, manufacturing method thereof, and pharmaceutical application of same | SLC10A6, TPMT, SLC6A6 | RAB9A 2246/4885NPC1 248/4885TSHR 1127/4885 |
| US-20200140423-A1 | Thiophene, Manufacturing Method Thereof, And Pharmaceutical Application Of Same | SLC10A6, TPMT, SLC6A6 | RAB9A 2246/4885NPC1 248/4885TSHR 1127/4885 |
| US-20070259852-A1 | BICYCLIC COMPOUNDS AND COMPOSITIONS AS PDF INHIBITORS | PDF, FDPS, DCTPP1 | RAB9A 1674/4885NPC1 761/4885TSHR 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.