Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LIPA | P38571 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1588109 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL1587116 | 1.00 | ALDH1A1 (0.58) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11531006 | 0.82 | KMT2A (0.51) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL13953865 | 0.79 | KMT2A (0.69) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL19826849 | 0.76 | KMT2A (0.47) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11529594 | 0.75 | HTT (0.61) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL30673515 | 0.73 | CYP1A2 (0.67) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL11528671 | 0.72 | TDP1 (0.69) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL10749123 | 0.71 | TDP1 (0.67) | ALDH1A1MAPK1ALOX15HSD17B10TSHR | |
| SCHEMBL18908562 | 0.71 | CYP1A2 (0.71) | ALDH1A1MAPK1ALOX15HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2073082-A | — | — | None | — | — | JP | disclosed |
| US-20210154202-A1 | SYNTHESIS OF DENTIMOL, AN ANTIGLAUCOMA DRUG | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2021-05-27 | — | — | US | disclosed |
| WO-2019202519-A1 | SYNTHESIS OF DENTIMOL, AN ANTIGLAUCOMA DRUG | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2019-10-24 | — | — | WO | disclosed |
| JP-H0273082-A | PRODUCTION OF OPTICALLY ACTIVE (S)-(+)-3-(2,3-EPOXYPROPOXY)-4-MORPHOLINO-1,2,5-THIADIAZOLE | YODOGAWA SEIYAKU KK | 1990-03-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154202-A1 | SYNTHESIS OF DENTIMOL, AN ANTIGLAUCOMA DRUG | PTGIR, PTGIS, DNM1L | ALDH1A1 2812/4885MAPK1 3820/4885ALOX15 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.