Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710599 | 0.87 | — | — | |
| Bicarbonate SCHEMBL28022646 | 0.79 | CYP2C19 (0.39) | CYP2C19TSHRALDH1A1HMGCRCHRM1 | |
| Bicarbonate SCHEMBL29015753 | 0.79 | CYP2C19 (0.39) | CYP2C19TSHRALDH1A1HMGCRCHRM1 | |
| Tert-Butyl Hydroperoxide SCHEMBL25265357 | 0.76 | ALDH1A1 (0.45) | CYP2C19ALDH1A1 | |
| SCHEMBL10949591 | 0.74 | — | — | |
| SCHEMBL1462566 | 0.71 | — | — | |
| SCHEMBL320683 | 0.71 | — | — | |
| Acetic Acid SCHEMBL7488788 | 0.71 | FFAR3 (0.41) | CYP2C19TSHRALDH1A1HMGCRCHRM1 | |
| Bicarbonate SCHEMBL4119077 | 0.67 | ALDH1A1 (0.44) | TSHRALDH1A1CYP2D6 | |
| Tert-Butyl Hydroperoxide SCHEMBL538709 | 0.67 | ALDH1A1 (0.69) | CYP2C19TSHRALDH1A1HMGCRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200388880-A1 | SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE ADDITIVE COMPOUNDS | ENEVATE CORPORATION | 2020-12-10 | — | — | US | claimed |
| JP-2110110-A | — | — | None | — | — | JP | disclosed |
| US-11742519-B2 | Silicon-based energy storage devices with electrolyte additive compounds | ENEVATE CORPORATION (US) | 2023-08-29 | — | — | US | disclosed |
| US-20200388880-A1 | SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE ADDITIVE COMPOUNDS | ENEVATE CORPORATION | 2020-12-10 | — | — | US | disclosed |
| JP-H02110110-A | POLYMERIZATION OR COPOLYMERIZATION OF ALKYLENE GLYCOL BIS(ALLYLCARBONATE) | SANKEN KAKO KK | 1990-04-23 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200388880-A1 | SILICON-BASED ENERGY STORAGE DEVICES WITH ELECTROLYTE ADDITIVE COMPOUNDS | SOST, CA1, DUOX2 | CYP2C19 2401/4885TSHR 4386/4885ALDH1A1 1727/4885 |
| US-11742519-B2 | Silicon-based energy storage devices with electrolyte additive compounds | SOST, CA1, DUOX2 | CYP2C19 2401/4885TSHR 4386/4885ALDH1A1 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.