SCHEMBL10338752

SCHEMBL10338752

CCCCCNC1C(=O)Nc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
NLRP3 Q96P20 1/20 0.57
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HTT P42858 1/20 0.43
CNR2 P34972 4/20 0.42
IDO1 P14902 2/20 0.41
MAPT P10636 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CACNB4 O00305 1/20 0.40
CACNA1A O00555 1/20 0.40
CACNA1G O43497 1/20 0.40
CACNG3 O60359 1/20 0.40
CACNA1F O60840 1/20 0.40
CACNA1H O95180 1/20 0.40
CACNB3 P54284 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9215471 0.83 ALDH1A1 (0.59) KDM4ENLRP3BCHEACHEALDH1A1
SCHEMBL1491212 0.77 KDM4E (0.47) KDM4ENLRP3ALDH1A1HSD17B10MEN1
Hydrochloric Acid SCHEMBL1491278 0.76 KDM4E (0.46) KDM4ENLRP3ALDH1A1HSD17B10MEN1
SCHEMBL9669489 0.75 BCHE (0.59) KDM4ENLRP3BCHEACHEALDH1A1
SCHEMBL24754644 0.74 IDO1 (0.46) KDM4ENLRP3ALDH1A1MEN1KMT2A
SCHEMBL5814656 0.74 IDO1 (0.64) KDM4ENLRP3ALDH1A1MEN1KMT2A
SCHEMBL10851169 0.73 IDO1 (0.62) KDM4ENLRP3IDO1MAPTL3MBTL1
SCHEMBL28414844 0.73 IDO1 (0.43) KDM4ENLRP3ALDH1A1IDO1MAPT
SCHEMBL3259666 0.73 BCHE (0.89) BCHEACHEMEN1KMT2A
SCHEMBL28019631 0.72 KDM4E (0.63) KDM4ENLRP3ALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2104778-A None JP disclosed
US-4921503-A FOR HAIR, INDOLINE DYES, NO OXIDIZER REQUIRED CLAIROL INCORPORATED (US) 1990-05-01 US disclosed
JP-H02104778-A NEW DYING COMPOSITION AND DYING BRISTOL MYERS SQUIBB CO 1990-04-17 JP disclosed