SCHEMBL10339295

SCHEMBL10339295

NC(=O)C(Cl)(Cl)c1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPT P10636 4/20 0.43
KDM4E B2RXH2 4/20 0.43
HPGD P15428 4/20 0.43
HSD17B10 Q99714 2/20 0.43
KCNN4 O15554 5/20 0.38
KIF11 P52732 1/20 0.37
KMT2A Q03164 1/20 0.36
CA12 O43570 2/20 0.36
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CA14 Q9ULX7 2/20 0.36
RAB9A P51151 2/20 0.36
ALOX15 P16050 2/20 0.36
NPC1 O15118 1/20 0.36
GMNN O75496 1/20 0.36
EGFR P00533 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449378 0.75 ALDH1A1 (0.56) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL30087647 0.75 ALDH1A1 (0.45) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL7190832 0.72 TSHR (0.56) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL9850834 0.72 ALDH1A1 (0.56) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL30475078 0.72 TSHR (0.56) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL21753685 0.72 KCNN4 (0.47) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL4556174 0.71 MAPT (0.56) TSHRTDP1MAPTHSD17B10KCNN4
SCHEMBL448585 0.71 TSHR (0.45) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL9397802 0.71 TSHR (0.45) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL28067112 0.70 ALDH1A1 (0.54) ALDH1A1TSHRTDP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2194019-A None JP disclosed
JP-H02194019-A FLAME-RESISTANT POLYCARBONATE AND ITS PRODUCTION ENICHEM TECNORESINE SPA 1990-07-31 JP disclosed