Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163394 | 0.83 | ALDH1A1 (0.47) | TSHRALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL448585 | 0.81 | TSHR (0.45) | TSHRALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL5898610 | 0.80 | NOS3 (0.43) | ALDH1A1KDM4EKMT2ALMNAKCNN4 | |
| SCHEMBL9397841 | 0.75 | PTGS2 (0.44) | TSHRALDH1A1TDP1KDM4EHPGD | |
| SCHEMBL449378 | 0.75 | ALDH1A1 (0.56) | TSHRALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL4030430 | 0.75 | MAPT (0.55) | TSHRTDP1MAPTKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL5252883 | 0.73 | MAPT (0.53) | TSHRTDP1MAPTKDM4EKMT2A | |
| SCHEMBL3793995 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL1822446 | 0.72 | TSHR (0.52) | TSHRALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL6672227 | 0.72 | TSHR (0.52) | TSHRALDH1A1TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5357033-A | Forming polyetherimmides having non-symmetrical polar radicals | GENERAL ELECTRIC COMPANY (US) | 1994-10-18 | — | — | US | disclosed |