SCHEMBL1033950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1204069	0.89	CYP3A4 (0.53)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1034303	0.89	VNN1 (0.48)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1035493	0.87	KMT2A (0.50)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1032557	0.85	CYP3A4 (0.55)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1035586	0.85	VNN1 (0.48)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1031391	0.85	VNN1 (0.43)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1035314	0.82	ADRA2C (0.49)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1033492	0.81	SORT1 (0.57)	SIGMAR1KDM4EALDH1A1VNN1GAA
	SCHEMBL1033966	0.80	CYP1A2 (0.57)	CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
	SCHEMBL1034307	0.80	NPC1 (0.45)	KDM4EALDH1A1HTTSMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.