SCHEMBL9360320

SCHEMBL9360320

CC(C)(NC(=O)Cc1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.55
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
ALDH1A1 P00352 2/20 0.53
HPGD P15428 2/20 0.51
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
RECQL P46063 1/20 0.50
EPHX2 P34913 1/20 0.50
MAPK1 P28482 1/20 0.49
CNR2 P34972 2/20 0.47
CNR1 P21554 1/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
SSTR4 P31391 1/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
AKR1B1 P15121 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11374247 0.88 ANO1 (0.49) P2RX7MEN1KMT2AALDH1A1CYP1A2
SCHEMBL11402011 0.85 MEN1 (0.53) P2RX7MEN1KMT2AALDH1A1HPGD
SCHEMBL10986259 0.83 MEN1 (0.59) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL23343879 0.81 P2RX7 (0.50) P2RX7KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL935057 0.81 SSTR4 (0.53) P2RX7KMT2AHDAC8HDAC6CYP1A2
SCHEMBL4345768 0.80 HPGD (0.51) P2RX7MEN1KMT2AHDAC8HDAC6
SCHEMBL9828810 0.80 SHMT1 (0.61) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL11196739 0.80 MEN1 (0.55) MEN1KMT2AHDAC8HDAC6ALDH1A1
SCHEMBL9364175 0.79 KCNJ5 (0.58) P2RX7MEN1KMT2AALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL4323383 0.79 SSTR4 (0.51) P2RX7KMT2AHDAC8HDAC6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4502883-A CONTAINING CHLORINE IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-03-05 US claimed
JP-57112304-A None JP disclosed
JP-57102803-A None JP disclosed
JP-57102802-A None JP disclosed
JP-57102801-A None JP disclosed
JP-57102806-A None JP disclosed
JP-6116218-A None JP disclosed
JP-55104240-A None JP disclosed
JP-H06116218-A N-@(3754/24)ALPHA,ALPHA-DIMETHYLBENZYL)PHENYLACETAMIDE DERIVATIVE MITSUBISHI PETROCHEM CO LTD 1994-04-26 JP disclosed
US-4502883-A CONTAINING CHLORINE IDEMITSU KOSAN COMPANY LIMITED (JP) 1985-03-05 US disclosed
JP-S57112304-A HERBICIDAL COMPOSITION IDEMITSU KOSAN CO LTD 1982-07-13 JP disclosed
JP-S57102806-A HERBICIDE COMPOSITION IDEMITSU KOSAN CO LTD 1982-06-26 JP disclosed
JP-S57102802-A HERBICIDE COMPOSITION IDEMITSU KOSAN CO LTD 1982-06-26 JP disclosed
JP-S57102803-A HERBICIDE COMPOSITION IDEMITSU KOSAN CO LTD 1982-06-26 JP disclosed
JP-S57102801-A HERBICIDE COMPOSITION IDEMITSU KOSAN CO LTD 1982-06-26 JP disclosed
JP-S55104240-A N-(ALPHA,ALPHA-DIMETHYLBENZYL)-ACETAMIDE DERIVATIVE AND HERBICIDE CONTAINING THE SAME IDEMITSU KOSAN CO LTD 1980-08-09 JP disclosed