Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718341 | 0.81 | MEN1 (0.39) | KIF11DYRK1AEPHX2SCN4AHRH4 | |
| SCHEMBL1030697 | 0.80 | PTGER1 (0.34) | KIF11DYRK1AEPHX2SCN4AHRH4 | |
| SCHEMBL27808915 | 0.75 | KIF11 (0.36) | KIF11DYRK1AEPHX2SCN4AHRH4 | |
| SCHEMBL1034046 | 0.75 | GSK3B (0.33) | KIF11DYRK1AEPHX2SCN4AHRH4 | |
| SCHEMBL1033112 | 0.74 | KIF11 (0.36) | KIF11DYRK1AEPHX2SCN4ALDHA | |
| SCHEMBL1031874 | 0.74 | KIF11 (0.36) | KIF11DYRK1AEPHX2SCN4ALDHA | |
| SCHEMBL716184 | 0.73 | KDM4E (0.40) | MAPTMEN1KMT2A | |
| SCHEMBL1033653 | 0.73 | ALDH1A1 (0.46) | KIF11DYRK1AMAPTMEN1KMT2A | |
| SCHEMBL1034624 | 0.73 | RORA (0.34) | DYRK1AEPHX2SCN4AHRH4MAPT | |
| SCHEMBL27829453 | 0.73 | ALDH1A1 (0.43) | KIF11DYRK1ALDHALDHBHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424917-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-2277874-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2018-06-27 | — | — | EP | disclosed |
| CN-104672220-A | Activating agent for peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO | 2015-06-03 | — | — | CN | disclosed |
| CN-102083810-B | Activator of peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO.,LTD. (JP) | 2014-10-29 | — | — | CN | disclosed |
| US-8648208-B2 | Activating agent for peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO. LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| CN-102083810-A | Activator of peroxisome proliferator activated receptor | NIPPON CHEMIPHAR CO | 2011-06-01 | — | — | CN | disclosed |
| US-20110098480-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO. LTD. (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2277874-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2011-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098480-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | PPARA, PPARG, PPARD | KIF11 3991/4885DYRK1A 4451/4885EPHX2 3401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.