Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340183 | 0.93 | TDP1 (0.49) | LMNASMN1; SMN2TDP1HDAC1HDAC2 | |
| SCHEMBL10340555 | 0.92 | HDAC1 (0.52) | LMNASMN1; SMN2TDP1HDAC1HDAC2 | |
| SCHEMBL10581036 | 0.87 | LMNA (0.52) | LMNASMN1; SMN2TDP1HDAC1HDAC2 | |
| SCHEMBL10340339 | 0.81 | TDP1 (0.47) | LMNASMN1; SMN2TDP1HDAC1HDAC2 | |
| SCHEMBL10086909 | 0.80 | ALDH1A1 (0.47) | LMNASMN1; SMN2HDAC1HDAC2KMT2A | |
| SCHEMBL18805587 | 0.79 | LMNA (0.62) | LMNASMN1; SMN2HDAC1HDAC2KMT2A | |
| SCHEMBL17686497 | 0.78 | LMNA (0.53) | LMNASMN1; SMN2HDAC1HDAC2KMT2A | |
| SCHEMBL19188184 | 0.78 | HDAC1 (0.47) | SMN1; SMN2HDAC1HDAC2KMT2AALDH1A1 | |
| SCHEMBL25413645 | 0.78 | ALDH1A1 (0.47) | HDAC1HDAC2KMT2AALDH1A1MAPT | |
| SCHEMBL25413647 | 0.78 | ALDH1A1 (0.47) | HDAC1HDAC2KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |