Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340183 | 0.96 | TDP1 (0.49) | HDAC1HDAC2TDP1LMNASMN1; SMN2 | |
| SCHEMBL10340548 | 0.92 | LMNA (0.50) | HDAC1HDAC2TDP1LMNASMN1; SMN2 | |
| SCHEMBL10340339 | 0.85 | TDP1 (0.47) | HDAC1HDAC2TDP1LMNASMN1; SMN2 | |
| SCHEMBL10581036 | 0.84 | LMNA (0.52) | HDAC1HDAC2TDP1LMNASMN1; SMN2 | |
| SCHEMBL10340184 | 0.77 | LMNA (0.50) | HDAC1HDAC2LMNASMN1; SMN2KMT2A | |
| SCHEMBL18805587 | 0.76 | LMNA (0.62) | HDAC1HDAC2LMNASMN1; SMN2MEN1 | |
| SCHEMBL10340557 | 0.76 | LMNA (0.49) | HDAC1HDAC2LMNASMN1; SMN2 | |
| SCHEMBL20648097 | 0.76 | EHMT2 (0.46) | HDAC1HDAC2LMNAMEN1KMT2A | |
| SCHEMBL405697 | 0.76 | EHMT2 (0.48) | HDAC1HDAC2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10340549 | 0.75 | LMNA (0.51) | HDAC1HDAC2LMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4841055-A | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4723012-A | Desmosine derivatives having a disulfide bond and preparation of artificial antigen using the same | JAPAN TOBACCO INC. (JP) | 1988-02-02 | — | — | US | disclosed |
| EP-0196007-A2 | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1986-10-01 | — | — | EP | disclosed |