Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340184 | 0.96 | LMNA (0.50) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL10340557 | 0.95 | LMNA (0.49) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL10581045 | 0.93 | LMNA (0.53) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL10340340 | 0.82 | LMNA (0.46) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL18805587 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL15927526 | 0.82 | ALDH1A1 (0.51) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL15927544 | 0.82 | LMNA (0.46) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL17686497 | 0.81 | LMNA (0.53) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL19245476 | 0.81 | ALDH1A1 (0.47) | LMNASMN1; SMN2HDAC1HDAC2NPC1 | |
| SCHEMBL19426340 | 0.80 | HDAC1 (0.44) | LMNASMN1; SMN2HDAC1HDAC2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |