Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340184 | 0.99 | LMNA (0.50) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10340549 | 0.95 | LMNA (0.51) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10581045 | 0.91 | LMNA (0.53) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10340340 | 0.83 | LMNA (0.46) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL18805587 | 0.80 | LMNA (0.62) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17686497 | 0.79 | LMNA (0.53) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL431027 | 0.78 | LMNA (0.67) | LMNASMN1; SMN2ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL7864966 | 0.78 | LMNA (0.67) | LMNASMN1; SMN2ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL2738376 | 0.78 | LMNA (0.49) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15927526 | 0.78 | ALDH1A1 (0.51) | LMNAHDAC1HDAC2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4841055-A | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4723012-A | Desmosine derivatives having a disulfide bond and preparation of artificial antigen using the same | JAPAN TOBACCO INC. (JP) | 1988-02-02 | — | — | US | disclosed |
| EP-0196007-A2 | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1986-10-01 | — | — | EP | disclosed |