Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340557 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2HDAC1HDAC2POLB | |
| SCHEMBL10340549 | 0.82 | LMNA (0.51) | LMNASMN1; SMN2HDAC1HDAC2POLB | |
| SCHEMBL10340184 | 0.81 | LMNA (0.50) | LMNASMN1; SMN2HDAC1HDAC2POLB | |
| SCHEMBL10340339 | 0.81 | TDP1 (0.47) | LMNASMN1; SMN2HDAC1HDAC2POLB | |
| SCHEMBL10340283 | 0.78 | LMNA (0.37) | LMNASMN1; SMN2HDAC1HDAC2MEN1 | |
| SCHEMBL10581045 | 0.78 | LMNA (0.53) | LMNASMN1; SMN2HDAC1HDAC2POLB | |
| SCHEMBL10340552 | 0.78 | LMNA (0.34) | LMNASMN1; SMN2HDAC1HDAC2MEN1 | |
| SCHEMBL1655486 | 0.74 | LMNA (0.38) | LMNASMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL26110443 | 0.73 | LMNA (0.48) | LMNASMN1; SMN2HDAC1HDAC2POLB | |
| SCHEMBL16132816 | 0.73 | ALDH1A1 (0.54) | LMNASMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4841055-A | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4723012-A | Desmosine derivatives having a disulfide bond and preparation of artificial antigen using the same | JAPAN TOBACCO INC. (JP) | 1988-02-02 | — | — | US | disclosed |
| EP-0196007-A2 | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1986-10-01 | — | — | EP | disclosed |