Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.34 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340609 | 0.87 | TSHR (0.45) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL10340538 | 0.75 | HTT (0.51) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL10621062 | 0.74 | MYC (0.38) | RIPK2NR4A3SLC9A1SLC9A2MAPK14 | |
| SCHEMBL10340567 | 0.74 | RIPK2 (0.47) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL10340615 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2TSHRALDH1A1NOTUM | |
| SCHEMBL10340610 | 0.73 | RIPK2 (0.64) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL10340641 | 0.72 | PTPN1 (0.50) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL10340690 | 0.72 | RIPK2 (0.48) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL10393453 | 0.71 | RIPK2 (0.42) | RIPK2MAPTPOLBL3MBTL1NR4A3 | |
| SCHEMBL14692428 | 0.70 | FGFR1 (0.51) | RIPK2MAPK14TSHRSCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |