Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.40 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340607 | 0.87 | RIPK2 (0.39) | TSHRNOTUMRIPK2ALDH1A1L3MBTL1 | |
| SCHEMBL14692428 | 0.83 | FGFR1 (0.51) | TSHRNOTUMRIPK2P2RX7HAVCR2 | |
| SCHEMBL8047299 | 0.81 | RIPK2 (0.56) | TSHRRIPK2P2RX7PARP1FGFR1 | |
| SCHEMBL10340615 | 0.78 | ALDH1A1 (0.48) | TSHRNOTUMALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL10894540 | 0.77 | MALT1 (0.45) | TSHRNOTUMP2RX7MEN1KMT2A | |
| SCHEMBL10340538 | 0.77 | HTT (0.51) | NOTUMRIPK2KMT2APARP1ALDH1A1 | |
| SCHEMBL6319872 | 0.76 | KEAP1 (0.61) | MEN1KMT2A | |
| SCHEMBL10340610 | 0.75 | RIPK2 (0.64) | RIPK2ALDH1A1L3MBTL1NR4A3POLB | |
| SCHEMBL10340641 | 0.74 | PTPN1 (0.50) | TSHRNOTUMRIPK2MEN1KMT2A | |
| SCHEMBL10340584 | 0.74 | NOTUM (0.45) | NOTUMRIPK2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-B1 | POLLEN FORMATION INHIBITING PYRAZOLES | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4775409-A | PREVENTING POLLEN FORMATION | ELI LILLY AND COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
| US-4666504-A | HYBRIDS | ELI LILLY AND COMPANY (US) | 1987-05-19 | — | — | US | disclosed |
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |