SCHEMBL1034091

SCHEMBL1034091

CCCC1CN[C@H](C(=O)O)C1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 2/20 0.64
DPP4 P27487 1/20 0.49
CYP1A2 P05177 3/20 0.48
ALOX15 P16050 3/20 0.48
CYP2C19 P33261 3/20 0.48
CYP2D6 P10635 3/20 0.48
SLC1A3 P43003 1/20 0.48
SLC1A2 P43004 1/20 0.48
SLC1A1 P43005 1/20 0.48
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
THRB P10828 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
GRIA3 P42263 1/20 0.41
GRIA4 P48058 1/20 0.41
GRIN1 Q05586 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3776510 1.00 ARG1 (0.64) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL26118062 1.00 ARG1 (0.64) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL11650754 1.00 ARG1 (0.64) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL5511790 0.89 ARG1 (0.60) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL3787271 0.89 ARG1 (0.60) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL4867875 0.87 ARG1 (0.58) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL3780786 0.87 ARG1 (0.58) ARG1DPP4CYP1A2ALOX15CYP2C19
SCHEMBL7442641 0.84 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL7411388 0.84 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL3781411 0.84 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11390662-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-07-19 US claimed
US-10329341-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-25 US claimed
US-20180030115-A1 COLLAGEN MIMICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-02-01 US claimed
US-9758569-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-09-12 US claimed
WO-2010127645-A2 THE METHOD OF BIOTECHNOLOGICAL PREPARATION OF LINCOMYCIN DERIVATIVES AND ITS USING INSTITUTE OF MICROBIOLOGY AS CR, V. V. I. (CZ) 2010-11-11 WO claimed
WO-2007139914-A2 COLLAGEN MIMICS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-12-06 WO claimed
US-20070275897-A1 Collagen mimics NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US claimed
CN-117987496-A Fermentation method for reducing lincomycin B component 宁夏泰益欣生物科技股份有限公司 2024-05-07 CN disclosed
CN-117305288-A EcTyrA protein mutant and application thereof in improving L-tyrosine yield 河南省健康元生物医药研究院有限公司 2023-12-29 CN disclosed
WO-2010127645-A3 THE METHOD OF BIOTECHNOLOGICAL PREPARATION OF LINCOMYCIN DERIVATIVES AND ITS USING INSTITUTE OF MICROBIOLOGY AS CR, V. V. I. (CZ) 2011-01-20 WO disclosed
US-7858741-B2 Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-12-28 US disclosed
WO-2010127645-A2 THE METHOD OF BIOTECHNOLOGICAL PREPARATION OF LINCOMYCIN DERIVATIVES AND ITS USING INSTITUTE OF MICROBIOLOGY AS CR, V. V. I. (CZ) 2010-11-11 WO disclosed
WO-2010127645-A2 THE METHOD OF BIOTECHNOLOGICAL PREPARATION OF LINCOMYCIN DERIVATIVES AND ITS USING INSTITUTE OF MICROBIOLOGY AS CR, V. V. I. (CZ) 2010-11-11 WO disclosed
US-20090264626-A1 STABILIZATION OF THE COLLAGEN TRIPLE HELIX BY O-METHYLATION OF HYDROXYPROLINE RESIDUES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-10-22 US disclosed
WO-2009100360-A1 STABILIZATION OF THE COLLAGEN TRIPLE HELIX BY O-METHYLATION OF HYDROXYPROLINE RESIDUES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2009-08-13 WO disclosed
US-4766110-A INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS RYAN JAMES W (US) 1988-08-23 US disclosed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 EP disclosed
US-RE29558-E Lincomycin analogs THE UPJOHN COMPANY (US) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264626-A1 STABILIZATION OF THE COLLAGEN TRIPLE HELIX BY O-METHYLATION OF HYDROXYPROLINE RESIDUES COL14A1, COL2A1, PLOD3 ARG1 67/4885DPP4 1346/4885CYP1A2 2169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.