SCHEMBL3781411

SCHEMBL3781411

CCC1CN[C@H](C(=O)O)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 2/20 0.58
CYP1A2 P05177 3/20 0.52
ALOX15 P16050 3/20 0.52
CYP2C19 P33261 3/20 0.52
CYP2D6 P10635 3/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
THRB P10828 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GRIN2D O15399 1/20 0.43
GRIN3B O60391 1/20 0.43
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
GRIA4 P48058 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2A Q12879 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7442641 1.00 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL29015450 1.00 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL7411388 1.00 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL31505386 1.00 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL3781408 1.00 ARG1 (0.58) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL24832759 0.84 ARG1 (0.54) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL11650754 0.84 ARG1 (0.64) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL1034091 0.84 ARG1 (0.64) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL3776510 0.84 ARG1 (0.64) ARG1CYP1A2ALOX15CYP2C19CYP2D6
SCHEMBL26118062 0.84 ARG1 (0.64) ARG1CYP1A2ALOX15CYP2C19CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11390662-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-07-19 US claimed
US-10329341-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-25 US claimed
US-20180030115-A1 COLLAGEN MIMICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-02-01 US claimed
US-9758569-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-09-12 US claimed
EP-3154568-A1 NON-CANONICAL INSULINS AND THEIR USES California Institute of Technology (US) 2017-04-19 EP claimed
WO-2015191705-A1 NON-CANONICAL INSULINS AND THEIR USES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2015-12-17 WO claimed
US-20150353619-A1 Non-Canonical Insulins and Their Uses CALIFORNIA INSTITUTE OF TECHNOLOGY 2015-12-10 US claimed
WO-2007139914-A2 COLLAGEN MIMICS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-12-06 WO claimed
US-20070275897-A1 Collagen mimics NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US claimed
CN-122055379-A Compounds containing one or more diboronate esters and related insulin analogues 普罗托莫科技公司 2026-05-15 CN disclosed
EP-4694932-A2 COMPOUNDS CONTAINING ONE OR MORE DIBORONATES AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2026-02-18 EP disclosed
US-20250249074-A1 GLUCOSE RESPONSIVE INSULINS PROTOMER TECHNOLOGIES INC. 2025-08-07 US disclosed
EP-4525919-A1 AROMATIC BORON-CONTAINING COMPOUNDS AND RELATED INSULIN ANALOGS Protomer Technologies Inc. (US) 2025-03-26 EP disclosed
CN-119677541-A Aromatic boron-containing compounds and related insulin analogues 原聚体科技公司 2025-03-21 CN disclosed
WO-1999002663-A1 ALKALINE XYLOGLUCANASE NOVO NORDISK A/S (DK) 1999-01-21 WO disclosed
US-4501901-A Method for making substituted prolines E. R. SQUIBB & SONS, INC. (US) 1985-02-26 US disclosed
US-4499287-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1985-02-12 US disclosed
US-4456761-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1984-06-26 US disclosed
US-4356182-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1982-10-26 US disclosed
US-4291040-A HYPOTENSIVE AGENTS E. R. SQUIBB & SONS, INC. (US) 1981-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250249074-A1 GLUCOSE RESPONSIVE INSULINS GLP1R, GPR119, IAPP ARG1 2202/4885CYP1A2 4240/4885ALOX15 4327/4885
US-20150353619-A1 Non-Canonical Insulins and Their Uses IAPP, IDE, INSR ARG1 415/4885CYP1A2 2895/4885ALOX15 1847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.