Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 9/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473901 | 0.83 | POLB (0.41) | TTR | |
| SCHEMBL10391880 | 0.81 | MAOA (0.46) | — | |
| SCHEMBL1636048 | 0.79 | PARP15 (0.55) | SRD5A2RXRARXRBRXRGMAPK14 | |
| SCHEMBL9740386 | 0.79 | PARP15 (0.55) | SRD5A2RXRARXRBRXRGMAPK14 | |
| SCHEMBL9290961 | 0.77 | SRD5A2 (0.55) | SRD5A2RXRARXRBRXRG | |
| SCHEMBL10390912 | 0.75 | MAOA (0.46) | — | |
| SCHEMBL16429183 | 0.75 | AKR1C3 (0.62) | SRD5A2MAPK14 | |
| SCHEMBL8746030 | 0.75 | RXRA (0.62) | LPAR1LPAR5SRD5A2RXRARXRB | |
| SCHEMBL8921736 | 0.75 | PARP15 (0.50) | SRD5A2RXRARXRBRXRGMAPK14 | |
| SCHEMBL336470 | 0.75 | SRD5A2 (0.61) | SRD5A2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317940-A3 | POLYCARBONAMIDES OF BIS (2-(4-CARBOXYPHENYL)HEXAFLUOROISOPROPYL) - DIPHENYL ETHER | HOECHST CELANESE CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |