SCHEMBL1034242

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1031934	0.91	EGLN1 (0.60)	ALDH1A1CYP2C9NPC1RAB9AEGLN1
	SCHEMBL1036245	0.83	ATR (0.58)	ALDH1A1ATRCYP2C9EGLN1ABL1
	SCHEMBL1034072	0.83	JAK2 (0.51)	ALDH1A1EGLN1ABL1SIRT2JAK2
	SCHEMBL1034164	0.83	SIRT2 (0.54)	ALDH1A1ATRCYP2C9NPC1RAB9A
	SCHEMBL1035548	0.83	PARP1 (0.65)	ALDH1A1CYP2C9NPC1RAB9AEGLN1
	SCHEMBL1034553	0.82	EPHX2 (0.54)	ALDH1A1NPC1RAB9AEGLN1SIRT2
	SCHEMBL1034842	0.82	SIRT2 (0.51)	ALDH1A1ATRCYP2C9NPC1RAB9A
	SCHEMBL1031026	0.82	ATR (0.57)	ALDH1A1ATRCYP2C9NPC1RAB9A
	SCHEMBL1033357	0.81	KMT2A (0.53)	ALDH1A1
	SCHEMBL1032167	0.81	MEN1 (0.48)	ALDH1A1NPC1RAB9AABL1SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.