SCHEMBL1034553

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1032356	0.90	CSF1R (0.54)	EPHX2EGLN1MAPTLMNAXBP1
	SCHEMBL1031934	0.88	EGLN1 (0.60)	EGLN1MAPTLMNASMN1; SMN2SIRT2
	SCHEMBL1030918	0.82	SGMS2 (0.52)	EGLN1MAPTSMN1; SMN2RXFP1SIRT2
	SCHEMBL1034242	0.82	ALDH1A1 (0.54)	EGLN1SIRT2NPC1RAB9AALDH1A1
	SCHEMBL1030617	0.81	ABL1 (0.52)	EGLN1MAPTLMNASMN1; SMN2NPSR1
	SCHEMBL1034318	0.80	FGFR4 (0.53)	EGLN1KDRFGFR4MAPKAPK2RXFP1
	SCHEMBL1035376	0.80	CSF1R (0.52)	EPHX2MAPTLMNAXBP1SMN1; SMN2
	SCHEMBL1031023	0.80	FGFR4 (0.55)	EGLN1SMN1; SMN2L3MBTL1FGFR4MAPKAPK2
	SCHEMBL1034072	0.80	JAK2 (0.51)	EGLN1MAPTLMNAXBP1SMN1; SMN2
	SCHEMBL1031619	0.80	SIRT2 (0.50)	EGLN1MAPTSMN1; SMN2BRAFSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.