Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621530 | 0.91 | KMT2A (0.60) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL8208952 | 0.89 | LMNA (0.77) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL23553004 | 0.89 | LMNA (0.77) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL1547982 | 0.89 | MAPT (0.57) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL19373814 | 0.89 | MAPT (0.70) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL27872796 | 0.87 | LMNA (0.74) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL27982583 | 0.87 | ALDH1A1 (0.77) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL9856921 | 0.86 | LMNA (0.72) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL15315055 | 0.85 | LMNA (0.71) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL6565192 | 0.84 | TSHR (0.60) | ALDH1A1MAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181404-B1 | PHTHALATE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-02-07 | — | — | EP | disclosed |
| EP-0181404-A1 | PHTHALATE COMPOUNDS | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-05-21 | — | — | EP | disclosed |