SCHEMBL10344670

SCHEMBL10344670

CN1OCC(=O)N(c2ccc(F)cc2)C1=O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
MGLL Q99685 1/20 0.43
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
ALDH1A1 P00352 6/20 0.39
HTT P42858 2/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP11B2 P19099 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9565725 0.74 MEN1 (0.49) MEN1KMT2APOLBGAAMGLL
SCHEMBL4887099 0.73 MEN1 (0.52) MEN1KMT2AGAAALDH1A1HTT
SCHEMBL29396063 0.73 MEN1 (0.52) MEN1KMT2AGAAALDH1A1HTT
SCHEMBL134538 0.73 MEN1 (0.52) MEN1KMT2AGAAALDH1A1HTT
SCHEMBL22281756 0.72 MGLL (0.54) MEN1KMT2APOLBGAAMGLL
SCHEMBL7164121 0.66 KMT2A (0.39) MEN1KMT2APOLBGAAALDH1A1
SCHEMBL19707626 0.65 MGLL (0.60) MEN1KMT2APOLBGAAMGLL
SCHEMBL28022213 0.65 KMT2A (0.64) MEN1KMT2APOLBGAAMGLL
SCHEMBL8884265 0.65 L3MBTL1 (0.64) MEN1KMT2APOLBGAAMGLL
SCHEMBL25201368 0.64 POLB (0.46) MEN1KMT2APOLBGAAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4789747-A BROAD LEAF PLANTS, GRASSES, WEEDS BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US disclosed
US-4761175-A M-anilido-urethanes and herbicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 US disclosed
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4632696-A POSTEMERGENCE, PREEMERGENCE APPLICATIONS BASF AKTIENGESELLSCHAFT (DE) 1986-12-30 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0037925-A1 Substituted pyridazinones, process for their preparation, herbicides containing them and their use as herbicides BASF Aktiengesellschaft (DE) 1981-10-21 EP disclosed
EP-0035712-A1 N-aryl(thiol) carbamates, process for their preparation and their use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1981-09-16 EP disclosed
EP-0032242-A1 4H-3,1-benzoxazine derivatives, process for their preparation and their use in inhibiting the growth of unwanted plants BASF Aktiengesellschaft (DE) 1981-07-22 EP disclosed
EP-0028355-A1 1,2-Oxazolylalkyl carbamates, their preparation, their use as herbicides, and herbicides BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed
EP-0027915-A1 Herbicidal agents based on diphenyl ethers and benzothiadiazinone dioxides or pyridinothiadiazinone dioxides, and their use BASF Aktiengesellschaft (DE) 1981-05-06 EP disclosed
EP-0025113-A1 5,6-Dihydro-1,2,4,6-thiatriazin(5)on-1.1-dioxides, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1981-03-18 EP disclosed
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed
EP-0024669-A1 Substituted N-benzoylanthranilic acid derivatives and their anhydro derivatives, process for their preparation, their use as herbicides and compositions therefor BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed
EP-0021324-A1 m-Anilido urethanes and herbicidal compositions which contain them BASF Aktiengesellschaft (DE) 1981-01-07 EP disclosed
EP-0019759-A1 N-arylthiolcarbamates, herbicides containing them and process for combating undesirable plant growth therewith BASF Aktiengesellschaft (DE) 1980-12-10 EP disclosed