Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22281756 | 0.88 | MGLL (0.54) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL5443754 | 0.83 | ELANE (0.57) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL5437358 | 0.83 | OPRK1 (0.56) | MEN1KMT2AGAAALDH1A1MGLL | |
| SCHEMBL11785882 | 0.81 | MAPT (0.44) | MEN1KMT2AGAAALDH1A1OPRK1 | |
| SCHEMBL9565728 | 0.81 | OPRK1 (0.55) | MEN1KMT2APOLBALDH1A1MGLL | |
| SCHEMBL13284550 | 0.80 | OPRK1 (0.58) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL11745569 | 0.79 | MGLL (0.53) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL12013775 | 0.77 | CA12 (0.59) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL2615294 | 0.76 | OPRK1 (0.76) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL11321678 | 0.75 | LMNA (0.64) | MEN1KMT2APOLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |