Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10766865 | 0.88 | KDM4E (0.47) | KDM4ELMNAALOX12MAPTPDK1 | |
| SCHEMBL10344854 | 0.88 | LMNA (0.45) | KDM4ELMNAALOX12MAPTPDK1 | |
| SCHEMBL9447348 | 0.85 | KDM4E (0.40) | KDM4ELMNAALOX12PDK1PDK2 | |
| SCHEMBL10809288 | 0.83 | MAPT (0.46) | KDM4EMAPTTDP1CA12CA1 | |
| SCHEMBL5305447 | 0.83 | ALDH1A1 (0.42) | KDM4EMAPTTDP1CA12CA1 | |
| SCHEMBL8806924 | 0.81 | CA12 (0.59) | KDM4ELMNAALOX12MAPTPDK1 | |
| SCHEMBL9024098 | 0.79 | LMNA (0.47) | KDM4ELMNAALOX12MAPTTDP1 | |
| SCHEMBL10606294 | 0.77 | LMNA (0.46) | KDM4ELMNAALOX12MAPTPDK1 | |
| SCHEMBL10808619 | 0.77 | CYP1A2 (0.50) | KDM4EMAPTTDP1KMT2AALDH1A1 | |
| SCHEMBL6826473 | 0.75 | CYP1A2 (0.51) | KDM4EMAPTTDP1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0216469-A2 | Process for the preparation of 5,6-dialkoxyanthranilic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-04-01 | — | — | EP | claimed |
| EP-0211588-B1 | PROCESS FOR PREPARING 2-ACYL-3,4-DIALKOXYANILINES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4883787-A | Process for preparing 2-acyl-3, 4-dialkoxyanilines | ORTHO PHARMACEUTICAL CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| US-4731480-A | Process for preparing 2-acyl-3,4-dialkoxyanilines | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |
| US-4658054-A | Process for the preparation of 5,6-dialkoxyanthranilic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0216469-A2 | Process for the preparation of 5,6-dialkoxyanthranilic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0211588-A1 | Process for preparing 2-acyl-3,4-dialkoxyanilines | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-02-25 | — | — | EP | disclosed |